The Si5351 library for avr-gcc that I've been promising for the last four posts is finally in a state where I feel comfortable releasing it, so I've posted it on GitHub. I think that the documentation posted on the README file and inside the code should be enough to get you going, but if you run into problems, please comment here or file an issue on the GitHub repository.
At this point it is very basic, but it will generate frequencies from 1 to 150 MHz on any of the three outputs of the Si5351A, and you can do stuff like turn the clocks on and off and change the drive strengths of the output drivers. More features will be added as time goes on, with the priority on things which will be needed to make a functioning amateur radio transceiver.
I'd like to point out something interesting that I've discovered about the parts that I've been working with. I ordered my Si5351A parts from Mouser (P/N 634-SI5351A-B02075GT). I never had any luck communicating with them on the datasheet-specified I2C address of 0x60; instead they need to be addressed at 0x6F. Thanks to the Bus Pirate and its built-in I2C address space scan macro, that didn't take me too long to figure out. I just chalked it up to yet another datasheet error (the Si5351 is riddled with problems), but it turns out that I may actually have some defective or custom parts which shouldn't have made it out to Mouser.
Over the last few days, I have been corresponding via email with Ian K3IMW, who has been having a horrible time getting his Si5351 to work. After he described his symptoms to me, I suggested that he try address 0x6F, and sure enough, that worked. What confounded him was that another ham he was in correspondence with was able to talk to the Si5351 using address 0x60. It turns out that those parts that work on 0x60 were from Digi-Key and both Ian and I obtained our parts from Mouser. So, the theory is that perhaps some custom parts accidentally made it out the door to Mouser. I will try to contact Mouser in the next day or two and see if perhaps they can get it straightened out with Silicon Labs.
The moral of the story to to pay attention to where you got your parts from if you are having problems with the Si5351. Once I can get my hands on some of the same P/N from a different vendor and can confirm that it does indeed work on address 0x60, I will make the change in the library. In the meantime, you may need to change that value yourself in the si5351.h file in order to get it working.